Background: Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is an assay used for investigating DNA-protein-binding or post-translational chromatin/histone ...
Data clustering methods have been proven to be a successful data mining technique in the analysis of gene expression data. The Cluster affinity search technique (CAST) developed b...
Abdelghani Bellaachia, David Portnoy, Yidong Chen,...
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...
Background: Currently, a number of bioinformatics methods are available to generate appropriate lists of genes from a microarray experiment. While these lists represent an accurat...
Melissa J. Morine, Jolene McMonagle, Sinead Toomey...
Background: Affymetrix GeneChips are a popular platform for performing whole-genome experiments on the transcriptome. There are a range of different calibration steps, and users a...
Andrew P. Harrison, Caroline E. Johnston, Christin...