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» Classification of microarray data using gene networks
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RECOMB
2007
Springer
16 years 4 months ago
An Efficient Method for Dynamic Analysis of Gene Regulatory Networks and in silico Gene Perturbation Experiments
With the increasing availability of experimental data on gene-gene and protein-protein interactions, modeling of gene regulatory networks has gained a special attention lately. To ...
Abhishek Garg, Ioannis Xenarios, Luis Mendoza, Gio...
BMCBI
2006
103views more  BMCBI 2006»
15 years 3 months ago
Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
Sébastien Lemieux
BMCBI
2005
141views more  BMCBI 2005»
15 years 3 months ago
Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis
Background: Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regenerati...
Nils E. Magnusson, Alessandra K. Cardozo, Mogens K...
BIOINFORMATICS
2006
135views more  BIOINFORMATICS 2006»
15 years 3 months ago
Effective similarity measures for expression profiles
It is commonly accepted that genes with similar expression profiles are functionally related. However, there are many ways one can measure the similarity of expression profiles, a...
Golan Yona, William Dirks, Shafquat Rahman, David ...
132
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BMCBI
2006
233views more  BMCBI 2006»
15 years 3 months ago
AbMiner: A bioinformatic resource on available monoclonal antibodies and corresponding gene identifiers for genomic, proteomic,
Background: Monoclonal antibodies are used extensively throughout the biomedical sciences for detection of antigens, either in vitro or in vivo. We, for example, have used them fo...
Sylvia M. Major, Satoshi Nishizuka, Daisaku Morita...