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» Classification of microarray data using gene networks
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146
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BMCBI
2007
143views more  BMCBI 2007»
15 years 3 months ago
Factor analysis for gene regulatory networks and transcription factor activity profiles
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Iosifina Pournara, Lorenz Wernisch
142
Voted
BMCBI
2008
138views more  BMCBI 2008»
15 years 3 months ago
Comparative analyses of bidirectional promoters in vertebrates
Background: Orthologous genes with deep phylogenetic histories are likely to retain similar regulatory features. In this report we utilize orthology assignments for pairs of genes...
Mary Qu Yang, James Taylor, Laura Elnitski
BMCBI
2008
136views more  BMCBI 2008»
15 years 3 months ago
A comparison of machine learning algorithms for chemical toxicity classification using a simulated multi-scale data model
Background: Bioactivity profiling using high-throughput in vitro assays can reduce the cost and time required for toxicological screening of environmental chemicals and can also r...
Richard Judson, Fathi Elloumi, R. Woodrow Setzer, ...
157
Voted
GECCO
2007
Springer
197views Optimization» more  GECCO 2007»
15 years 9 months ago
Computational intelligence techniques: a study of scleroderma skin disease
This paper presents an analysis of microarray gene expression data from patients with and without scleroderma skin disease using computational intelligence and visual data mining ...
Julio J. Valdés, Alan J. Barton
158
Voted
SDM
2009
SIAM
251views Data Mining» more  SDM 2009»
16 years 20 days ago
High Performance Parallel/Distributed Biclustering Using Barycenter Heuristic.
Biclustering refers to simultaneous clustering of objects and their features. Use of biclustering is gaining momentum in areas such as text mining, gene expression analysis and co...
Alok N. Choudhary, Arifa Nisar, Waseem Ahmad, Wei-...