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» Classification of microarray data using gene networks
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BIOINFORMATICS
2010
109views more  BIOINFORMATICS 2010»
15 years 3 months ago
Phylogenetic networks do not need to be complex: using fewer reticulations to represent conflicting clusters
Phylogenetic trees are widely used to display estimates of how groups of species evolved. Each phylogenetic tree can be seen as a collection of clusters, subgroups of the species ...
Leo van Iersel, Steven Kelk, Regula Rupp, Daniel H...
142
Voted
BMCBI
2010
113views more  BMCBI 2010»
15 years 3 months ago
A classification model for distinguishing copy number variants from cancer-related alterations
Background: Both somatic copy number alterations (CNAs) and germline copy number variants (CNVs) that are prevalent in healthy individuals can appear as recurrent changes in compa...
Irina Ostrovnaya, Gouri Nanjangud, Adam B. Olshen
144
Voted
BMCBI
2010
113views more  BMCBI 2010»
15 years 3 months ago
Class prediction for high-dimensional class-imbalanced data
Background: The goal of class prediction studies is to develop rules to accurately predict the class membership of new samples. The rules are derived using the values of the varia...
Rok Blagus, Lara Lusa
ICML
2008
IEEE
16 years 4 months ago
Statistical models for partial membership
We present a principled Bayesian framework for modeling partial memberships of data points to clusters. Unlike a standard mixture model which assumes that each data point belongs ...
Katherine A. Heller, Sinead Williamson, Zoubin Gha...
CSB
2005
IEEE
141views Bioinformatics» more  CSB 2005»
15 years 9 months ago
Joint Genomic and Metabolomic Analysis of Toxic Dose-Response Experiments
A methodology has been implemented for analyzing microarray and NMR spectral data obtained from the same set of toxic-exposure dose-response experiments. The NMR spectra additiona...
Gary L. Jahns, Nicholas J. DelRaso, Mark P. Westri...