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» Classification of microarray data using gene networks
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BMCBI
2008
128views more  BMCBI 2008»
15 years 4 months ago
Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate reg
Background: Gene expression measurements from breast cancer (BrCa) tumors are established clinical predictive tools to identify tumor subtypes, identify patients showing poor/good...
David D. Smith, Pål Sætrom, Ola R. Sn&...
BMCBI
2006
86views more  BMCBI 2006»
15 years 4 months ago
Identification of QTLs controlling gene expression networks defined a priori
Background: Gene expression microarrays allow the quantification of transcript accumulation for many or all genes in a genome. This technology has been utilized for a range of inv...
Daniel J. Kliebenstein, Marilyn A. L. West, Hans v...
BIOINFORMATICS
2005
72views more  BIOINFORMATICS 2005»
15 years 4 months ago
Use of within-array replicate spots for assessing differential expression in microarray experiments
Motivation. Spotted arrays are often printed with probes in duplicate or triplicate, but current methods for assessing differential expression are not able to make full use of the...
Gordon K. Smyth, Joëlle Michaud, Hamish S. Sc...
BMCBI
2006
132views more  BMCBI 2006»
15 years 4 months ago
Comprehensive quality control utilizing the prehybridization third-dye image leads to accurate gene expression measurements by c
Background: Gene expression profiling using microarrays has become an important genetic tool. Spotted arrays prepared in academic labs have the advantage of low cost and high desi...
Xujing Wang, Shuang Jia, Lisa Meyer, Bixia Xiang, ...
BMCBI
2007
120views more  BMCBI 2007»
15 years 4 months ago
Transcript-based redefinition of grouped oligonucleotide probe sets using AceView: High-resolution annotation for microarrays
Background: Extracting biological information from high-density Affymetrix arrays is a multi-step process that begins with the accurate annotation of microarray probes. Shortfalls...
Jun Lu, Joseph C. Lee, Marc L. Salit, Margaret C. ...