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BMCBI
2010
165views more  BMCBI 2010»
14 years 9 months ago
Multivariate meta-analysis of proteomics data from human prostate and colon tumours
Background: There is a vast need to find clinically applicable protein biomarkers as support in cancer diagnosis and tumour classification. In proteomics research, a number of met...
Lina Hultin Rosenberg, Bo Franzén, Gert Aue...
BMCBI
2005
100views more  BMCBI 2005»
14 years 9 months ago
EvDTree: structure-dependent substitution profiles based on decision tree classification of 3D environments
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
Jean-Christophe Gelly, Laurent Chiche, Jér&...
KDD
2003
ACM
190views Data Mining» more  KDD 2003»
15 years 10 months ago
Distance-enhanced association rules for gene expression
We introduce a novel data mining technique for the analysis of gene expression. Gene expression is the effective production of the protein that a gene encodes. We focus on the cha...
Aleksandar Icev, Carolina Ruiz, Elizabeth F. Ryder
106
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LION
2009
Springer
114views Optimization» more  LION 2009»
15 years 4 months ago
Substitution Matrices and Mutual Information Approaches to Modeling Evolution
Abstract. Substitution matrices are at the heart of Bioinformatics: sequence alignment, database search, phylogenetic inference, protein family classication are based on Blosum, P...
Stephan Kitchovitch, Yuedong Song, Richard C. van ...
BMCBI
2010
153views more  BMCBI 2010»
14 years 9 months ago
Metamotifs - a generative model for building families of nucleotide position weight matrices
Background: Development of high-throughput methods for measuring DNA interactions of transcription factors together with computational advances in short motif inference algorithms...
Matias Piipari, Thomas A. Down, Tim J. P. Hubbard