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BMCBI
2010
154views more  BMCBI 2010»
15 years 4 months ago
An algorithm for automated closure during assembly
Background: Finishing is the process of improving the quality and utility of draft genome sequences generated by shotgun sequencing and computational assembly. Finishing can invol...
Sergey Koren, Jason R. Miller, Brian Walenz, Grang...
BMCBI
2007
265views more  BMCBI 2007»
15 years 4 months ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
BMCBI
2008
154views more  BMCBI 2008»
15 years 4 months ago
GeNESiS: gene network evolution simulation software
Background: There has been a lot of interest in recent years focusing on the modeling and simulation of Gene Regulatory Networks (GRNs). However, the evolutionary mechanisms that ...
Anton Kratz, Masaru Tomita, Arun Krishnan
BMCBI
2008
108views more  BMCBI 2008»
15 years 4 months ago
A nonparametric model for quality control of database search results in shotgun proteomics
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
Jiyang Zhang, Jianqi Li, Xin Liu, Hongwei Xie, Yun...
BMCBI
2008
112views more  BMCBI 2008»
15 years 4 months ago
A general modeling and visualization tool for comparing different members of a group: application to studying tau-mediated regul
Background: Innumerable biological investigations require comparing collections of molecules, cells or organisms to one another with respect to one or more of their properties. Al...
Arnab Bhattacharya, Sasha Levy, Adria LeBoeuf, Mic...