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BMCBI
2007
140views more  BMCBI 2007»
14 years 10 months ago
From genes to functional classes in the study of biological systems
Background: With the popularisation of high-throughput techniques, the need for procedures that help in the biological interpretation of results has increased enormously. Recently...
Fátima Al-Shahrour, Leonardo Arbiza, Hern&a...
BMCBI
2007
94views more  BMCBI 2007»
14 years 9 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
BMCBI
2002
109views more  BMCBI 2002»
14 years 9 months ago
Kangaroo - A pattern-matching program for biological sequences
Background: Biologists are often interested in performing a simple database search to identify proteins or genes that contain a well-defined sequence pattern. Many databases do no...
Doron Betel, Christopher W. V. Hogue
NAR
2000
94views more  NAR 2000»
14 years 9 months ago
INE: a rice genome database with an integrated map view
The Rice Genome Research Program (RGP) launched a large-scale rice genome sequencing in 1998 aimed at decoding all genetic information in rice. A new genome database called INE (I...
Katsumi Sakata, Baltazar A. Antonio, Yoshiyuki Muk...
BMCBI
2011
14 years 1 months ago
ENGINES: exploring single nucleotide variation in entire human genomes
Background: Next generation ultra-sequencing technologies are starting to produce extensive quantities of data from entire human genome or exome sequences, and therefore new softw...
Jorge Amigo, Antonio Salas, Christopher Phillips