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BMCBI
2005
109views more  BMCBI 2005»
15 years 18 days ago
Genome comparison without alignment using shortest unique substrings
Background: Sequence comparison by alignment is a fundamental tool of molecular biology. In this paper we show how a number of sequence comparison tasks, including the detection o...
Bernhard Haubold, Nora Pierstorff, Friedrich M&oum...
115
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PSB
2003
15 years 2 months ago
MAP: Searching Large Genome Databases
A number of biological applications require comparison of large genome strings. Current techniques suffer from both disk I/O and computational cost because of extensive memory req...
Tamer Kahveci, Ambuj K. Singh
108
Voted
BMCBI
2007
163views more  BMCBI 2007»
15 years 21 days ago
Use of genomic DNA control features and predicted operon structure in microarray data analysis: ArrayLeaRNA - a Bayesian approac
Background: Microarrays are widely used for the study of gene expression; however deciding on whether observed differences in expression are significant remains a challenge. Resul...
Carmen Pin, Mark Reuter
109
Voted
NAR
2006
177views more  NAR 2006»
15 years 19 days ago
PUMA2 - grid-based high-throughput analysis of genomes and metabolic pathways
The PUMA2 system (available at http://compbio.mcs. 10 anl.gov/puma2) is an interactive, integrated bioinformatics environment for high-throughput genetic sequence analysis and met...
Natalia Maltsev, Elizabeth M. Glass, Dinanath Sula...
BIB
2008
113views more  BIB 2008»
15 years 25 days ago
Identification of replication origins in prokaryotic genomes
The availability of hundreds of complete bacterial genomes has created new challenges and simultaneously opportunities for bioinformatics. In the area of statistical analysis of g...
Natalia V. Sernova, Mikhail S. Gelfand