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BMCBI
2008
105views more  BMCBI 2008»
15 years 5 months ago
Novel computational methods for increasing PCR primer design effectiveness in directed sequencing
Background: Polymerase chain reaction (PCR) is used in directed sequencing for the discovery of novel polymorphisms. As the first step in PCR directed sequencing, effective PCR pr...
Kelvin Li, Anushka Brownley, Timothy B. Stockwell,...
BMCBI
2006
112views more  BMCBI 2006»
15 years 5 months ago
Distill: a suite of web servers for the prediction of one-, two- and three-dimensional structural features of proteins
Background: We describe Distill, a suite of servers for the prediction of protein structural features: secondary structure; relative solvent accessibility; contact density; backbo...
Davide Baù, Alberto J. M. Martin, Catherine...
BMCBI
2007
115views more  BMCBI 2007»
15 years 5 months ago
Local comparison of protein structures highlights cases of convergent evolution in analogous functional sites
Background: We performed an exhaustive search for local structural similarities in an ensemble of non-redundant protein functional sites. With the purpose of finding new examples ...
Gabriele Ausiello, Daniele Peluso, Allegra Via, Ma...
JASIS
2006
96views more  JASIS 2006»
15 years 5 months ago
Learning to classify documents according to genre
Genre or style analysis can be used to improve results achieved using standard IR techniques. A genre class is a group of documents that are written in a similar style. Genre clas...
Aidan Finn, Nicholas Kushmerick
NAR
2011
256views Computer Vision» more  NAR 2011»
14 years 8 months ago
COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
COSMIC (http://www.sanger.ac.uk/cosmic) curates comprehensive information on somatic mutations in human cancer. Release v48 (July 2010) describes over 136 000 coding mutations in ...
Simon A. Forbes, Nidhi Bindal, Sally Bamford, Char...