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BMCBI
2004
207views more  BMCBI 2004»
14 years 9 months ago
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrep-resen
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
Davide Corà, Ferdinando Di Cunto, Paolo Pro...
BMCBI
2010
144views more  BMCBI 2010»
14 years 9 months ago
Super-sparse principal component analyses for high-throughput genomic data
Background: Principal component analysis (PCA) has gained popularity as a method for the analysis of highdimensional genomic data. However, it is often difficult to interpret the ...
Donghwan Lee, Woojoo Lee, Youngjo Lee, Yudi Pawita...
BMCBI
2006
131views more  BMCBI 2006»
14 years 9 months ago
Hybridization interactions between probesets in short oligo microarrays lead to spurious correlations
Background: Microarrays measure the binding of nucleotide sequences to a set of sequence specific probes. This information is combined with annotation specifying the relationship ...
Michal J. Okoniewski, Crispin J. Miller
KDD
2006
ACM
142views Data Mining» more  KDD 2006»
15 years 10 months ago
Automatic mining of fruit fly embryo images
We present FEMine, an automatic system for image-based gene expression analysis. We perform experiments on the largest publicly available collection of Drosophila ISH (in situ hyb...
Jia-Yu Pan, André G. R. Balan, Eric P. Xing...
BMCBI
2007
103views more  BMCBI 2007»
14 years 9 months ago
A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance
Background: The Significance Analysis of Microarrays (SAM) is a popular method for detecting significantly expressed genes and controlling the false discovery rate (FDR). Recently...
Shunpu Zhang