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BMCBI
2006
203views more  BMCBI 2006»
14 years 9 months ago
Independent component analysis reveals new and biologically significant structures in micro array data
Background: An alternative to standard approaches to uncover biologically meaningful structures in micro array data is to treat the data as a blind source separation (BSS) problem...
Attila Frigyesi, Srinivas Veerla, David Lindgren, ...
BMCBI
2006
138views more  BMCBI 2006»
14 years 9 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
BMCBI
2010
104views more  BMCBI 2010»
14 years 4 months ago
A systematic study of genome context methods: calibration, normalization and combination
Background: Genome context methods have been introduced in the last decade as automatic methods to predict functional relatedness between genes in a target genome using the patter...
Luciana Ferrer, Joseph M. Dale, Peter D. Karp
BMCBI
2005
178views more  BMCBI 2005»
14 years 9 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
GECCO
2005
Springer
156views Optimization» more  GECCO 2005»
15 years 3 months ago
Extraction of informative genes from microarray data
Identification of those genes that might anticipate the clinical behavior of different types of cancers is challenging due to availability of a smaller number of patient samples...
Topon Kumar Paul, Hitoshi Iba