A central issue in molecular biology is understanding the regulatory mechanisms that control gene expression. The recent flood of genomic and postgenomic data opens the way for co...
Background: Microarray time series studies are essential to understand the dynamics of molecular events. In order to limit the analysis to those genes that change expression over ...
Barbara Di Camillo, Gianna Toffolo, Sreekumaran K....
Background: We provide a systematic study of the sources of variability in expression profiling data using 56 RNAs isolated from human muscle biopsies (34 Affymetrix MuscleChip ar...
Marina Bakay, Yi-Wen Chen, Rehannah H. A. Borup, P...
Background: Expressed sequence tag (EST) collections are composed of a high number of single-pass, redundant, partial sequences, which need to be processed, clustered, and annotat...
The problem of overlapping clustering, where a point is allowed to belong to multiple clusters, is becoming increasingly important in a variety of applications. In this paper, we ...