Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Background: Extracting biological information from high-density Affymetrix arrays is a multi-step process that begins with the accurate annotation of microarray probes. Shortfalls...
Jun Lu, Joseph C. Lee, Marc L. Salit, Margaret C. ...
Some tasks in a dataspace (a loose collection of heterogeneous data sources) require integration of fine-grained data from diverse sources. This work is often done by end users kn...
David W. Archer, Lois M. L. Delcambre, David Maier
Principal component analysis (PCA) is a widely used statistical technique for unsupervised dimension reduction. K-means clustering is a commonly used data clustering for unsupervi...
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...