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BMCBI
2008
128views more  BMCBI 2008»
15 years 4 months ago
Efficient computation of absent words in genomic sequences
Background: Analysis of sequence composition is a routine task in genome research. Organisms are characterized by their base composition, dinucleotide relative abundance, codon us...
Julia Herold, Stefan Kurtz, Robert Giegerich
BMCBI
2008
160views more  BMCBI 2008»
15 years 4 months ago
Feature selection environment for genomic applications
Background: Feature selection is a pattern recognition approach to choose important variables according to some criteria in order to distinguish or explain certain phenomena (i.e....
Fabrício Martins Lopes, David Correa Martin...
BMCBI
2008
124views more  BMCBI 2008»
15 years 4 months ago
Alignment of protein structures in the presence of domain motions
Background: Structural alignment is an important step in protein comparison. Well-established methods exist for solving this problem under the assumption that the structures under...
Roberto Mosca, Barbara Brannetti, Thomas R. Schnei...
BMCBI
2008
102views more  BMCBI 2008»
15 years 4 months ago
Improving protein function prediction methods with integrated literature data
Background: Determining the function of uncharacterized proteins is a major challenge in the post-genomic era due to the problem's complexity and scale. Identifying a protein...
Aaron Gabow, Sonia M. Leach, William A. Baumgartne...
BMCBI
2006
239views more  BMCBI 2006»
15 years 4 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
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