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BMCBI
2006
160views more  BMCBI 2006»
14 years 11 months ago
MIMAS: an innovative tool for network-based high density oligonucleotide microarray data management and annotation
Background: The high-density oligonucleotide microarray (GeneChip) is an important tool for molecular biological research aiming at large-scale detection of small nucleotide polym...
Leandro Hermida, Olivier Schaad, Philippe Demougin...
BMCBI
2006
144views more  BMCBI 2006»
14 years 11 months ago
More robust detection of motifs in coexpressed genes by using phylogenetic information
Background: Several motif detection algorithms have been developed to discover overrepresented motifs in sets of coexpressed genes. However, in a noisy gene list, the number of ge...
Pieter Monsieurs, Gert Thijs, Abeer A. Fadda, Sigr...
BMCBI
2006
131views more  BMCBI 2006»
14 years 11 months ago
Hybridization interactions between probesets in short oligo microarrays lead to spurious correlations
Background: Microarrays measure the binding of nucleotide sequences to a set of sequence specific probes. This information is combined with annotation specifying the relationship ...
Michal J. Okoniewski, Crispin J. Miller
SIGOPS
2008
119views more  SIGOPS 2008»
14 years 11 months ago
Project Kittyhawk: building a global-scale computer: Blue Gene/P as a generic computing platform
This paper describes Project Kittyhawk, an undertaking at IBM Research to explore the construction of a nextgeneration platform capable of hosting many simultaneous web-scale work...
Jonathan Appavoo, Volkmar Uhlig, Amos Waterland
103
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SP
2008
IEEE
122views Security Privacy» more  SP 2008»
14 years 11 months ago
Large-scale phylogenetic analysis on current HPC architectures
Abstract. Phylogenetic inference is considered a grand challenge in Bioinformatics due to its immense computational requirements. The increasing popularity and availability of larg...
Michael Ott, Jaroslaw Zola, Srinivas Aluru, Andrew...