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» Clustering cancer gene expression data: a comparative study
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124
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BMCBI
2008
134views more  BMCBI 2008»
14 years 11 months ago
Identification of transcription factor contexts in literature using machine learning approaches
Background: Availability of information about transcription factors (TFs) is crucial for genome biology, as TFs play a central role in the regulation of gene expression. While man...
Hui Yang, Goran Nenadic, John A. Keane
ISBI
2009
IEEE
15 years 6 months ago
Optimal Illumination Patterns for Fluorescence Tomography
Fluorescence tomography has become increasingly popular for detecting molecular targets for imaging gene expression and other cellular processes in vivo in small animal studies. I...
Joyita Dutta, Sangtae Ahn, Anand A. Joshi, Richard...
87
Voted
ICML
2008
IEEE
16 years 13 days ago
Expectation-maximization for sparse and non-negative PCA
We study the problem of finding the dominant eigenvector of the sample covariance matrix, under additional constraints on the vector: a cardinality constraint limits the number of...
Christian D. Sigg, Joachim M. Buhmann
BMCBI
2008
132views more  BMCBI 2008»
14 years 11 months ago
The SeqWord Genome Browser: an online tool for the identification and visualization of atypical regions of bacterial genomes thr
Background: Data mining in large DNA sequences is a major challenge in microbial genomics and bioinformatics. Oligonucleotide usage (OU) patterns provide a wealth of information f...
Hamilton Ganesan, Anna S. Rakitianskaia, Colin F. ...
87
Voted
CLUSTER
2009
IEEE
15 years 6 months ago
Analyzing massive astrophysical datasets: Can Pig/Hadoop or a relational DBMS help?
Abstract— As the datasets used to fuel modern scientific discovery grow increasingly large, they become increasingly difficult to manage using conventional software. Parallel d...
Sarah Loebman, Dylan Nunley, YongChul Kwon, Bill H...