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» Clustering gene expression patterns
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BMCBI
2007
136views more  BMCBI 2007»
14 years 10 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette
BMCBI
2007
103views more  BMCBI 2007»
14 years 10 months ago
eQTL Viewer: visualizing how sequence variation affects genome-wide transcription
Background: Expression Quantitative Trait Locus (eQTL) mapping methods have been used to identify the genetic basis of gene expression variations. To map eQTL, thousands of expres...
Wei Zou, David L. Aylor, Zhao-Bang Zeng
SIAMCOMP
2008
123views more  SIAMCOMP 2008»
14 years 10 months ago
Approximation Algorithms for Biclustering Problems
One of the main goals in the analysis of microarray data is to identify groups of genes and groups of experimental conditions (including environments, individuals, and tissues) tha...
Lusheng Wang, Yu Lin, Xiaowen Liu
PR
2006
116views more  PR 2006»
14 years 10 months ago
Shared farthest neighbor approach to clustering of high dimensionality, low cardinality data
Clustering algorithms are routinely used in biomedical disciplines, and are a basic tool in bioinformatics. Depending on the task at hand, there are two most popular options, the ...
Stefano Rovetta, Francesco Masulli
BMCBI
2010
153views more  BMCBI 2010»
14 years 10 months ago
Starr: Simple Tiling ARRay analysis of Affymetrix ChIP-chip data
Background: Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is an assay used for investigating DNA-protein-binding or post-translational chromatin/histone ...
Benedikt Zacher, Pei Fen Kuan, Achim Tresch