MicroRNAs (miRNAs) represent an important class of small non-coding RNAs (sRNAs) that regulate gene expression by targeting messenger RNAs. However, assigning miRNAs to their regu...
eraction networks. In this abstract, we extend this approach by mining functional flow patterns for the purpose of detecting small-sized modules for specific functions. Methods Our...
Background: Recent biological discoveries have shown that clustering large datasets is essential for better understanding biology in many areas. Spectral clustering in particular ...
Habil Zare, Parisa Shooshtari, Arvind Gupta, Ryan ...
The problem of elucidating the functional significance of genes is a key challenge of modern science. Solving this problem can lead to fundamental advancements across multiple are...
Alan Shimoide, Ilmi Yoon, Megumi Fuse, Holly C. Be...
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...