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» Clustering gene expression patterns
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BMCBI
2008
135views more  BMCBI 2008»
14 years 10 months ago
Identification of a small optimal subset of CpG sites as bio-markers from high-throughput DNA methylation profiles
Background: DNA methylation patterns have been shown to significantly correlate with different tissue types and disease states. High-throughput methylation arrays enable large-sca...
Hailong Meng, Edward Lenn Murrelle, Guoya Li
BMCBI
2004
111views more  BMCBI 2004»
14 years 9 months ago
Aggregation of topological motifs in the Escherichia coli transcriptional regulatory network
Background: Transcriptional regulation of cellular functions is carried out through a complex network of interactions among transcription factors and the promoter regions of genes...
Radu Dobrin, Qasim K. Beg, Albert-Lászl&oac...
NAR
2008
97views more  NAR 2008»
14 years 9 months ago
Database resources of the National Center for Biotechnology Information
In addition to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for th...
David L. Wheeler, Tanya Barrett, Dennis A. Benson,...
BMCBI
2010
122views more  BMCBI 2010»
14 years 4 months ago
Functional enrichment analyses and construction of functional similarity networks with high confidence function prediction by PF
Background: A new paradigm of biological investigation takes advantage of technologies that produce large high throughput datasets, including genome sequences, interactions of pro...
Troy Hawkins, Meghana Chitale, Daisuke Kihara
CIBCB
2009
IEEE
14 years 11 months ago
Steady-state analysis of genetic regulatory networks modeled by nonlinear ordinary differential equations
Although Ordinary Differential Equations (ODEs) have been used to model Genetic Regulatory Networks (GRNs) in many previous works, their steady-state behaviors are not well studied...
Haixin Wang, Lijun Qian, Edward R. Dougherty