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BIOINFORMATICS
2006
129views more  BIOINFORMATICS 2006»
14 years 9 months ago
Predicting methylation status of CpG islands in the human brain
Motivation: Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulatio...
Fang Fang, Shicai Fan, Xuegong Zhang, Michael Q. Z...
BMCBI
2008
132views more  BMCBI 2008»
14 years 9 months ago
The SeqWord Genome Browser: an online tool for the identification and visualization of atypical regions of bacterial genomes thr
Background: Data mining in large DNA sequences is a major challenge in microbial genomics and bioinformatics. Oligonucleotide usage (OU) patterns provide a wealth of information f...
Hamilton Ganesan, Anna S. Rakitianskaia, Colin F. ...
ICDM
2008
IEEE
146views Data Mining» more  ICDM 2008»
15 years 4 months ago
Hunting for Coherent Co-clusters in High Dimensional and Noisy Datasets
Clustering problems often involve datasets where only a part of the data is relevant to the problem, e.g., in microarray data analysis only a subset of the genes show cohesive exp...
Meghana Deodhar, Joydeep Ghosh, Gunjan Gupta, Hyuk...
IMSCCS
2006
IEEE
15 years 3 months ago
Frequency Distribution of TATA Box and Extension Sequences on Human Promoters
Background: TATA box is one of the most important transcription factor binding sites. But the exact sequences of TATA box are still not very clear. Results: In this study, we cond...
Wei Shi, Wanlei Zhou
BMCBI
2005
161views more  BMCBI 2005»
14 years 9 months ago
Non-linear mapping for exploratory data analysis in functional genomics
Background: Several supervised and unsupervised learning tools are available to classify functional genomics data. However, relatively less attention has been given to exploratory...
Francisco Azuaje, Haiying Wang, Alban Chesneau