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» Clustering gene expression patterns
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BMCBI
2004
113views more  BMCBI 2004»
14 years 9 months ago
Influence of microarrays experiments missing values on the stability of gene groups by hierarchical clustering
Background: Microarray technologies produced large amount of data. The hierarchical clustering is commonly used to identify clusters of co-expressed genes. However, microarray dat...
Alexandre G. de Brevern, Serge A. Hazout, Alain Ma...
RECOMB
2006
Springer
15 years 10 months ago
Identification and Evaluation of Functional Modules in Gene Co-expression Networks
Abstract. Identifying gene functional modules is an important step towards elucidating gene functions at a global scale. In this paper, we introduce a simple method to construct ge...
Jianhua Ruan, Weixiong Zhang
BMCBI
2010
92views more  BMCBI 2010»
14 years 10 months ago
Integrating gene expression and GO classification for PCA by preclustering
Background: Gene expression data can be analyzed by summarizing groups of individual gene expression profiles based on GO annotation information. The mean expression profile per g...
Jorn R. de Haan, Ester Piek, René C. van Sc...
BIOCOMP
2006
14 years 11 months ago
A Heuristic Approach to Scoring Gene Clustering Algorithms
In the past decades, many clustering algorithms have been proposed for the analysis of gene expression data, but little guidance is available to help choose among them. Given the ...
Longde Yin, Chun-Hsi Huang
IMSCCS
2007
IEEE
15 years 4 months ago
Multi-dimensional Cluster Misclassification Test for Pathway Differential Analysis of Diabetes
Gene pathway can be defined as a group of genes that interact with each other to perform some biological processes. Along with the efforts to identify the individual genes that pl...
Lily R. Liang, Vinay Mandal, Yi Lu, Deepak Kumar