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» Clustering gene expression patterns
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BMCBI
2007
118views more  BMCBI 2007»
14 years 10 months ago
A new advance in alternative splicing databases: from catalogue to detailed analysis of regulation of expression and function of
Background: Most human genes produce several transcripts with different exon contents by using alternative promoters, alternative polyadenylation sites and alternative splice site...
Pierre de la Grange, Martin Dutertre, Margot Corre...
DKE
2007
101views more  DKE 2007»
14 years 10 months ago
Parameterized pattern queries
We introduce parameterized pattern queries as a new paradigm to extend traditional pattern expressions over sequence databases. A parameterized pattern is essentially a string mad...
Cédric du Mouza, Philippe Rigaux, Michel Sc...
BMCBI
2002
136views more  BMCBI 2002»
14 years 9 months ago
Making sense of EST sequences by CLOBBing them
Background: Expressed sequence tags (ESTs) are single pass reads from randomly selected cDNA clones. They provide a highly cost-effective method to access and identify expressed g...
John Parkinson, David B. Guiliano, Mark L. Blaxter
BIOCOMP
2008
14 years 11 months ago
Reverse Engineering Module Networks by PSO-RNN Hybrid Modeling
Background: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reas...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2004
150views more  BMCBI 2004»
14 years 9 months ago
Cross-species comparison significantly improves genome-wide prediction of cis-regulatory modules in Drosophila
Background: The discovery of cis-regulatory modules in metazoan genomes is crucial for understanding the connection between genes and organism diversity. It is important to quanti...
Saurabh Sinha, Mark D. Schroeder, Ulrich Unnerstal...