Background: The continuous flow of EST data remains one of the richest sources for discoveries in modern biology. The first step in EST data mining is usually associated with EST ...
The biological interpretation of large-scale gene expression data is one of the challenges in current bioinformatics. The state-of-theart approach is to perform clustering and then...
Italo Zoppis, Daniele Merico, Marco Antoniotti, Bu...
The growth of bioinformatics has resulted in datasets with new characteristics. These datasets typically contain a large number of columns and a small number of rows. For example,...
Feng Pan, Gao Cong, Anthony K. H. Tung, Jiong Yang...
—In this paper, we have modified a constrained clustering algorithm to perform exploratory analysis on gene expression data using prior knowledge presented in the form of constr...
Erliang Zeng, Chengyong Yang, Tao Li, Giri Narasim...
Clustering methods are a useful and common first step in gene expression studies, but the results may be hard to interpret. We bring in explicitly an indicator of which genes tie ...