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BMCBI
2008
117views more  BMCBI 2008»
14 years 11 months ago
New resampling method for evaluating stability of clusters
Background: Hierarchical clustering is a widely applied tool in the analysis of microarray gene expression data. The assessment of cluster stability is a major challenge in cluste...
Irina Gana Dresen, Tanja Boes, Johannes Hüsin...
BMCBI
2006
138views more  BMCBI 2006»
14 years 11 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
AIIA
2009
Springer
15 years 6 months ago
Ontology-Driven Co-clustering of Gene Expression Data
Abstract. The huge volume of gene expression data produced by microarrays and other high-throughput techniques has encouraged the development of new computational techniques to eva...
Francesca Cordero, Ruggero G. Pensa, Alessia Visco...
BMCBI
2005
112views more  BMCBI 2005»
14 years 11 months ago
Visualization methods for statistical analysis of microarray clusters
Background: The most common method of identifying groups of functionally related genes in microarray data is to apply a clustering algorithm. However, it is impossible to determin...
Matthew A. Hibbs, Nathaniel C. Dirksen, Kai Li, Ol...
BMCBI
2007
174views more  BMCBI 2007»
14 years 11 months ago
Inferring activity changes of transcription factors by binding association with sorted expression profiles
Background: The identification of transcription factors (TFs) associated with a biological process is fundamental to understanding its regulatory mechanisms. From microarray data,...
Chao Cheng, Xiting Yan, Fengzhu Sun, Lei M. Li