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BIOINFORMATICS
2006
135views more  BIOINFORMATICS 2006»
14 years 9 months ago
Effective similarity measures for expression profiles
It is commonly accepted that genes with similar expression profiles are functionally related. However, there are many ways one can measure the similarity of expression profiles, a...
Golan Yona, William Dirks, Shafquat Rahman, David ...
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BMCBI
2010
129views more  BMCBI 2010»
14 years 9 months ago
A temporal precedence based clustering method for gene expression microarray data
Background: Time-course microarray experiments can produce useful data which can help in understanding the underlying dynamics of the system. Clustering is an important stage in m...
Ritesh Krishna, Chang-Tsun Li, Vicky Buchanan-Woll...
BMCBI
2010
115views more  BMCBI 2010»
14 years 9 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
BMCBI
2008
134views more  BMCBI 2008»
14 years 9 months ago
Clustering cancer gene expression data: a comparative study
Background The use of clustering methods for the discovery of cancer subtypes has drawn a great deal of attention in the scientific community. While bioinformaticians have propose...
Marcílio Carlos Pereira de Souto, Ivan G. C...
BMCBI
2008
122views more  BMCBI 2008»
14 years 9 months ago
A practical comparison of two K-Means clustering algorithms
Background: Data clustering is a powerful technique for identifying data with similar characteristics, such as genes with similar expression patterns. However, not all implementat...
Gregory A. Wilkin, Xiuzhen Huang