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IJDMB
2008
117views more  IJDMB 2008»
14 years 9 months ago
Scoring and summarising gene product clusters using the Gene Ontology
: We propose an approach for quantifying the biological relatedness between gene products, based on their properties, and measure their similarities using exclusively statistical N...
Spiridon C. Denaxas, Christos Tjortjis
BIBE
2004
IEEE
160views Bioinformatics» more  BIBE 2004»
15 years 1 months ago
A Time Series Analysis of Microarray Data
As the capture and analysis of single-time-point microarray expression data becomes routine, investigators are turning to time-series expression data to investigate complex gene r...
Selnur Erdal, Ozgur Ozturk, David L. Armbruster, H...
BMCBI
2010
115views more  BMCBI 2010»
14 years 9 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2008
202views more  BMCBI 2008»
14 years 9 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2006
142views more  BMCBI 2006»
14 years 9 months ago
Improving the Performance of SVM-RFE to Select Genes in Microarray Data
Background: Recursive Feature Elimination is a common and well-studied method for reducing the number of attributes used for further analysis or development of prediction models. ...
Yuanyuan Ding, Dawn Wilkins