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BMCBI
2006
136views more  BMCBI 2006»
14 years 9 months ago
Metric for Measuring the Effectiveness of Clustering of DNA Microarray Expression
Background: The recent advancement of microarray technology with lower noise and better affordability makes it possible to determine expression of several thousand genes simultane...
Raja Loganantharaj, Satish Cheepala, John Clifford
RECOMB
2007
Springer
15 years 10 months ago
Learning Gene Regulatory Networks via Globally Regularized Risk Minimization
Learning the structure of a gene regulatory network from time-series gene expression data is a significant challenge. Most approaches proposed in the literature to date attempt to ...
Yuhong Guo, Dale Schuurmans
BMCBI
2005
113views more  BMCBI 2005»
14 years 9 months ago
Pathway level analysis of gene expression using singular value decomposition
Background: A promising direction in the analysis of gene expression focuses on the changes in expression of specific predefined sets of genes that are known in advance to be rela...
John K. Tomfohr, Jun Lu, Thomas B. Kepler
BIBE
2007
IEEE
151views Bioinformatics» more  BIBE 2007»
14 years 11 months ago
On the Effectiveness of Constraints Sets in Clustering Genes
—In this paper, we have modified a constrained clustering algorithm to perform exploratory analysis on gene expression data using prior knowledge presented in the form of constr...
Erliang Zeng, Chengyong Yang, Tao Li, Giri Narasim...
BMCBI
2010
154views more  BMCBI 2010»
14 years 9 months ago
Candidate gene prioritization by network analysis of differential expression using machine learning approaches
Background: Discovering novel disease genes is still challenging for diseases for which no prior knowledge - such as known disease genes or disease-related pathways - is available...
Daniela Nitsch, Joana P. Gonçalves, Fabian ...