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BMCBI
2006
166views more  BMCBI 2006»
14 years 9 months ago
bioNMF: a versatile tool for non-negative matrix factorization in biology
Background: In the Bioinformatics field, a great deal of interest has been given to Non-negative matrix factorization technique (NMF), due to its capability of providing new insig...
Alberto D. Pascual-Montano, Pedro Carmona-Saez, Mo...
BMCBI
2008
124views more  BMCBI 2008»
14 years 10 months ago
Literature-aided meta-analysis of microarray data: a compendium study on muscle development and disease
Background: Comparative analysis of expression microarray studies is difficult due to the large influence of technical factors on experimental outcome. Still, the identified diffe...
Rob Jelier, Peter A. C. 't Hoen, Ellen Sterrenburg...
BMCBI
2006
138views more  BMCBI 2006»
14 years 9 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
JMLR
2010
163views more  JMLR 2010»
14 years 4 months ago
Dense Message Passing for Sparse Principal Component Analysis
We describe a novel inference algorithm for sparse Bayesian PCA with a zero-norm prior on the model parameters. Bayesian inference is very challenging in probabilistic models of t...
Kevin Sharp, Magnus Rattray
BMCBI
2010
193views more  BMCBI 2010»
14 years 4 months ago
Mayday - integrative analytics for expression data
Background: DNA Microarrays have become the standard method for large scale analyses of gene expression and epigenomics. The increasing complexity and inherent noisiness of the ge...
Florian Battke, Stephan Symons, Kay Nieselt