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BMCBI
2011
14 years 4 months ago
Investigating the effect of paralogs on microarray gene-set analysis
Background: In order to interpret the results obtained from a microarray experiment, researchers often shift focus from analysis of individual differentially expressed genes to an...
Andre J. Faure, Cathal Seoighe, Nicola J. Mulder
JMLR
2006
96views more  JMLR 2006»
14 years 9 months ago
Rearrangement Clustering: Pitfalls, Remedies, and Applications
Given a matrix of values in which the rows correspond to objects and the columns correspond to features of the objects, rearrangement clustering is the problem of rearranging the ...
Sharlee Climer, Weixiong Zhang
RECOMB
2002
Springer
15 years 10 months ago
Probabilistic hierarchical clustering for biological data
Biological data, such as gene expression profiles or protein sequences, is often organized in a hierarchy of classes, where the instances assigned to "nearby" classes in...
Eran Segal, Daphne Koller
DEXAW
2004
IEEE
167views Database» more  DEXAW 2004»
15 years 1 months ago
BioMap: Gene Family based Integration of Heterogeneous Biological Databases Using AutoMed Metadata
This paper presents an extensible architecture that can be used to support the integration of biological data sets. Biological research frequently requires this kind of synthesis....
Michael Maibaum, Galia Rimon, Christine A. Orengo,...
BMCBI
2007
143views more  BMCBI 2007»
14 years 10 months ago
Factor analysis for gene regulatory networks and transcription factor activity profiles
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Iosifina Pournara, Lorenz Wernisch