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BMCBI
2006
149views more  BMCBI 2006»
14 years 11 months ago
Curation of viral genomes: challenges, applications and the way forward
Background: Whole genome sequence data is a step towards generating the 'parts list' of life to understand the underlying principles of Biocomplexity. Genome sequencing ...
Urmila Kulkarni-Kale, Shriram Bhosle, G. Sunitha M...
BMCBI
2006
85views more  BMCBI 2006»
14 years 11 months ago
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
Rui Jiang, Hua Yang, Fengzhu Sun, Ting Chen
NAR
2011
257views Computer Vision» more  NAR 2011»
14 years 2 months ago
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
An essential prerequisite for any systems-level understanding of cellular functions is to correctly uncover and annotate all functional interactions among proteins in the cell. To...
Damian Szklarczyk, Andrea Franceschini, Michael Ku...
NAR
2011
260views Computer Vision» more  NAR 2011»
14 years 2 months ago
ASD: a comprehensive database of allosteric proteins and modulators
Allostery is the most direct, rapid and efficient way of regulating protein function, ranging from the control of metabolic mechanisms to signaltransduction pathways. However, an ...
Zhimin Huang, Liang Zhu, Yan Cao, Geng Wu, Xinyi L...
IPMI
2007
Springer
16 years 10 days ago
Shape Regression Machine
Abstract. We present a machine learning approach called shape regression machine (SRM) to segmenting in real time an anatomic structure that manifests a deformable shape in a medic...
Shaohua Kevin Zhou, Dorin Comaniciu