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BMCBI
2006
249views more  BMCBI 2006»
14 years 9 months ago
Gene functional similarity search tool (GFSST)
Background: With the completion of the genome sequences of human, mouse, and other species and the advent of high throughput functional genomic research technologies such as biomi...
Peisen Zhang, Jinghui Zhang, Huitao Sheng, James J...
BMCBI
2006
133views more  BMCBI 2006»
14 years 9 months ago
Choosing negative examples for the prediction of protein-protein interactions
The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
Asa Ben-Hur, William Stafford Noble
BMCBI
2006
108views more  BMCBI 2006»
14 years 9 months ago
Gene function classification using Bayesian models with hierarchy-based priors
We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
Babak Shahbaba, Radford M. Neal
BMCBI
2006
133views more  BMCBI 2006»
14 years 9 months ago
An integrated approach to the prediction of domain-domain interactions
Background: The development of high-throughput technologies has produced several large scale protein interaction data sets for multiple species, and significant efforts have been ...
Hyunju Lee, Minghua Deng, Fengzhu Sun, Ting Chen
CORR
2006
Springer
103views Education» more  CORR 2006»
14 years 9 months ago
AS Relationships: Inference and Validation
Research on performance, robustness, and evolution of the global Internet is fundamentally handicapped without accurate and thorough knowledge of the nature and structure of the c...
Xenofontas A. Dimitropoulos, Dmitri V. Krioukov, M...