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BMCBI
2004
96views more  BMCBI 2004»
14 years 11 months ago
Gene finding in novel genomes
Background: Computational gene prediction continues to be an important problem, especially for genomes with little experimental data. Results: I introduce the SNAP gene finder whi...
Ian Korf
BMCBI
2005
97views more  BMCBI 2005»
14 years 11 months ago
Evolutionary distance estimation and fidelity of pair wise sequence alignment
Background: Evolutionary distances are a critical measure in comparative genomics and molecular evolutionary biology. A simulation study was used to examine the effect of alignmen...
Michael S. Rosenberg
BMCBI
2006
143views more  BMCBI 2006»
14 years 11 months ago
Fast estimation of the difference between two PAM/JTT evolutionary distances in triplets of homologous sequences
Background: The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of t...
Christophe Dessimoz, Manuel Gil, Adrian Schneider,...
BMCBI
2010
120views more  BMCBI 2010»
14 years 11 months ago
Estimating true evolutionary distances under rearrangements, duplications, and losses
Background: The rapidly increasing availability of whole-genome sequences has enabled the study of whole-genome evolution. Evolutionary mechanisms based on genome rearrangements h...
Yu Lin, Vaibhav Rajan, Krister M. Swenson, Bernard...
BIB
2008
88views more  BIB 2008»
14 years 11 months ago
MEGA: A biologist-centric software for evolutionary analysis of DNA and protein sequences
The Molecular Evolutionary Genetics Analysis (MEGA) software is a desktop application designed for comparative analysis of homologous gene sequences either from multigene families...
Sudhir Kumar, Masatoshi Nei, Joel Dudley, Koichiro...