Sciweavers

241 search results - page 6 / 49
» Columba: an integrated database of proteins, structures, and...
Sort
View
BMCBI
2006
120views more  BMCBI 2006»
14 years 9 months ago
Integrating protein structures and precomputed genealogies in the Magnum database: Examples with cellular retinoid binding prote
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...
Michael E. Bradley, Steven A. Benner
BMCBI
2008
112views more  BMCBI 2008»
14 years 9 months ago
GlycomeDB - integration of open-access carbohydrate structure databases
Background: Although carbohydrates are the third major class of biological macromolecules, after proteins and DNA, there is neither a comprehensive database for carbohydrate struc...
René Ranzinger, Stephan Herget, Thomas Wett...
JIB
2006
106views more  JIB 2006»
14 years 9 months ago
A structural keystone for drug design
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...
Kristian Rother, Mathias Dunkel, Elke Michalsky, S...
BMCBI
2007
108views more  BMCBI 2007»
14 years 9 months ago
Integrating sequence and structural biology with DAS
Background: The Distributed Annotation System (DAS) is a network protocol for exchanging biological data. It is frequently used to share annotations of genomes and protein sequenc...
Andreas Prlic, Thomas A. Down, Eugene Kulesha, Rob...
BMCBI
2008
141views more  BMCBI 2008»
14 years 9 months ago
The development of PIPA: an integrated and automated pipeline for genome-wide protein function annotation
Background: Automated protein function prediction methods are needed to keep pace with high-throughput sequencing. With the existence of many programs and databases for inferring ...
Chenggang Yu, Nela Zavaljevski, Valmik Desai, Seth...