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» Combined Gene Selection Methods for Microarray Data Analysis
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BMCBI
2008
97views more  BMCBI 2008»
15 years 3 months ago
MCM-test: a fuzzy-set-theory-based approach to differential analysis of gene pathways
Background: Gene pathway can be defined as a group of genes that interact with each other to perform some biological processes. Along with the efforts to identify the individual g...
Lily R. Liang, Vinay Mandal, Yi Lu, Deepak Kumar
ICCSA
2005
Springer
15 years 8 months ago
A Penalized Likelihood Estimation on Transcriptional Module-Based Clustering
In this paper, we propose a new clustering procedure for high dimensional microarray data. Major difficulty in cluster analysis of microarray data is that the number of samples to ...
Ryo Yoshida, Seiya Imoto, Tomoyuki Higuchi
BMCBI
2010
115views more  BMCBI 2010»
15 years 3 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
BMCBI
2007
148views more  BMCBI 2007»
15 years 3 months ago
Computation of significance scores of unweighted Gene Set Enrichment Analyses
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...
Andreas Keller, Christina Backes, Hans-Peter Lenho...
BMCBI
2010
170views more  BMCBI 2010»
15 years 3 months ago
Integrative analysis of gene expression and copy number alterations using canonical correlation analysis
Background: With the rapid development of new genetic measurement methods, several types of genetic alterations can be quantified in a high-throughput manner. While the initial fo...
Charlotte Soneson, Henrik Lilljebjörn, Thoas ...