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» Combined Gene Selection Methods for Microarray Data Analysis
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BMCBI
2010
132views more  BMCBI 2010»
15 years 3 months ago
Consistency, comprehensiveness, and compatibility of pathway databases
Background: It is necessary to analyze microarray experiments together with biological information to make better biological inferences. We investigate the adequacy of current bio...
Donny Soh, Difeng Dong, Yike Guo, Limsoon Wong
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BMCBI
2006
110views more  BMCBI 2006»
15 years 3 months ago
Design of a combinatorial DNA microarray for protein-DNA interaction studies
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...
Julian Mintseris, Michael B. Eisen
BMCBI
2006
131views more  BMCBI 2006»
15 years 3 months ago
Hybridization interactions between probesets in short oligo microarrays lead to spurious correlations
Background: Microarrays measure the binding of nucleotide sequences to a set of sequence specific probes. This information is combined with annotation specifying the relationship ...
Michal J. Okoniewski, Crispin J. Miller
BMCBI
2008
166views more  BMCBI 2008»
15 years 3 months ago
Learning transcriptional regulatory networks from high throughput gene expression data using continuous three-way mutual informa
Background: Probability based statistical learning methods such as mutual information and Bayesian networks have emerged as a major category of tools for reverse engineering mecha...
Weijun Luo, Kurt D. Hankenson, Peter J. Woolf
BMCBI
2006
128views more  BMCBI 2006»
15 years 3 months ago
An interactive tool for visualization of relationships between gene expression profiles
Background: Application of phenetic methods to gene expression analysis proved to be a successful approach. Visualizing the results in a 3-dimentional space may further enhance th...
Peter Ruzanov, Steven J. M. Jones