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» Combining Affymetrix microarray results
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172
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BMCBI
2004
146views more  BMCBI 2004»
15 years 3 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
WABI
2009
Springer
155views Bioinformatics» more  WABI 2009»
15 years 10 months ago
A Markov Classification Model for Metabolic Pathways
Background: This paper considers the problem of identifying pathways through metabolic networks that relate to a specific biological response. Our proposed model, HME3M, first ide...
Timothy Hancock, Hiroshi Mamitsuka
130
Voted
IMSCCS
2006
IEEE
15 years 9 months ago
Clustering of Gene Expression Data: Performance and Similarity Analysis
Background: DNA Microarray technology is an innovative methodology in experimental molecular biology, which has produced huge amounts of valuable data in the profile of gene expre...
Longde Yin, Chun-Hsi Huang
160
Voted
BMCBI
2010
153views more  BMCBI 2010»
15 years 3 months ago
GOAL: A software tool for assessing biological significance of genes groups
Background: Modern high throughput experimental techniques such as DNA microarrays often result in large lists of genes. Computational biology tools such as clustering are then us...
Alain B. Tchagang, Alexander Gawronski, Hugo B&eac...
138
Voted
BMCBI
2007
134views more  BMCBI 2007»
15 years 3 months ago
A framework for significance analysis of gene expression data using dimension reduction methods
Background: The most popular methods for significance analysis on microarray data are well suited to find genes differentially expressed across predefined categories. However, ide...
Lars Halvor Gidskehaug, Endre Anderssen, Arnar Fla...