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» Combining haplotypers
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98
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BMCBI
2007
95views more  BMCBI 2007»
15 years 17 days ago
Haplotype-based score test for linkage in nuclear families
Background: To look for genetic linkage between angiotensin-I converting enzyme(ACE) gene and hypertension in a Korean adolescent cohort, we developed a powerful test using the co...
Chung Mo Nam, Dae Ryong Kang, Jinheum Kim
37
Voted
CORR
2007
Springer
108views Education» more  CORR 2007»
15 years 12 days ago
Combining haplotypers
Matti Kääriäinen, Niels Landwehr, S...
BMCBI
2008
138views more  BMCBI 2008»
15 years 17 days ago
Inference of haplotypic phase and missing genotypes in polyploid organisms and variable copy number genomic regions
Background: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organ...
Shu-Yi Su, Jonathan White, David J. Balding, Lachl...
135
Voted
BMCBI
2010
125views more  BMCBI 2010»
15 years 17 days ago
Haplotype allelic classes for detecting ongoing positive selection
Background: Natural selection eliminates detrimental and favors advantageous phenotypes. This process leaves characteristic signatures in underlying genomic segments that can be r...
Julie Hussin, Philippe Nadeau, Jean-Françoi...
BMCBI
2007
165views more  BMCBI 2007»
15 years 17 days ago
Direct maximum parsimony phylogeny reconstruction from genotype data
Background: Maximum parsimony phylogenetic tree reconstruction from genetic variation data is a fundamental problem in computational genetics with many practical applications in p...
Srinath Sridhar, Fumei Lam, Guy E. Blelloch, R. Ra...