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BMCBI
2008
92views more  BMCBI 2008»
14 years 9 months ago
OpenMS - An open-source software framework for mass spectrometry
Background: Mass spectrometry is an essential analytical technique for high-throughput analysis in proteomics and metabolomics. The development of new separation techniques, preci...
Marc Sturm, Andreas Bertsch, Clemens Gröpl, A...
BMCBI
2010
100views more  BMCBI 2010»
14 years 9 months ago
Efficiency clustering for low-density microarrays and its application to QPCR
Background: Pathway-targeted or low-density arrays are used more and more frequently in biomedical research, particularly those arrays that are based on quantitative real-time PCR...
Eric F. Lock, Ryan Ziemiecki, J. S. Marron, Dirk P...
BMCBI
2007
156views more  BMCBI 2007»
14 years 9 months ago
Large-scale clustering of CAGE tag expression data
Background: Recent analyses have suggested that many genes possess multiple transcription start sites (TSSs) that are differentially utilized in different tissues and cell lines. ...
Kazuro Shimokawa, Yuko Okamura-Oho, Takio Kurita, ...
BMCBI
2008
175views more  BMCBI 2008»
14 years 9 months ago
Comprehensive inventory of protein complexes in the Protein Data Bank from consistent classification of interfaces
Background: Protein-protein interactions are ubiquitous and essential for all cellular processes. High-resolution X-ray crystallographic structures of protein complexes can reveal...
Andrew J. Bordner, Andrey A. Gorin
BMCBI
2007
165views more  BMCBI 2007»
14 years 9 months ago
Direct maximum parsimony phylogeny reconstruction from genotype data
Background: Maximum parsimony phylogenetic tree reconstruction from genetic variation data is a fundamental problem in computational genetics with many practical applications in p...
Srinath Sridhar, Fumei Lam, Guy E. Blelloch, R. Ra...
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