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BMCBI
2010
136views more  BMCBI 2010»
15 years 5 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
144
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BMCBI
2007
97views more  BMCBI 2007»
15 years 5 months ago
Relating destabilizing regions to known functional sites in proteins
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...
Benoit H. Dessailly, Marc F. Lensink, Shoshana J. ...
BMCBI
2008
130views more  BMCBI 2008»
15 years 5 months ago
Structural descriptor database: a new tool for sequence-based functional site prediction
Background: The Structural Descriptor Database (SDDB) is a web-based tool that predicts the function of proteins and functional site positions based on the structural properties o...
Juliana S. Bernardes, Jorge H. Fernandez, Ana Tere...
BMCBI
2008
118views more  BMCBI 2008»
15 years 5 months ago
Virtual screening of GPCRs: An in silico chemogenomics approach
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Laurent Jacob, Brice Hoffmann, Véronique St...
143
Voted
CCR
2008
118views more  CCR 2008»
15 years 5 months ago
A generic language for application-specific flow sampling
Flow records gathered by routers provide valuable coarse-granularity traffic information for several measurement-related network applications. However, due to high volumes of traf...
Harsha V. Madhyastha, Balachander Krishnamurthy
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