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BMCBI
2007
134views more  BMCBI 2007»
14 years 9 months ago
PLAN: a web platform for automating high-throughput BLAST searches and for managing and mining results
Background: BLAST searches are widely used for sequence alignment. The search results are commonly adopted for various functional and comparative genomics tasks such as annotating...
Ji He, Xinbin Dai, Xuechun Zhao
BMCBI
2007
99views more  BMCBI 2007»
14 years 9 months ago
Orthogonal projections to latent structures as a strategy for microarray data normalization
Background: During generation of microarray data, various forms of systematic biases are frequently introduced which limits accuracy and precision of the results. In order to prop...
Max Bylesjö, Daniel Eriksson, Andreas Sjö...
BMCBI
2010
151views more  BMCBI 2010»
14 years 9 months ago
Using diffusion distances for flexible molecular shape comparison
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
Yu-Shen Liu, Qi Li, Guo-Qin Zheng, Karthik Ramani,...
BMCBI
2007
101views more  BMCBI 2007»
14 years 9 months ago
Statistical validation of megavariate effects in ASCA
Background: Innovative extensions of (M) ANOVA gain common ground for the analysis of designed metabolomics experiments. ASCA is such a multivariate analysis method; it has succes...
Daniel J. Vis, Johan A. Westerhuis, Age K. Smilde,...
BMCBI
2008
138views more  BMCBI 2008»
14 years 9 months ago
Inference of haplotypic phase and missing genotypes in polyploid organisms and variable copy number genomic regions
Background: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organ...
Shu-Yi Su, Jonathan White, David J. Balding, Lachl...