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» Comparative genome assembly
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BMCBI
2005
132views more  BMCBI 2005»
15 years 14 days ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
109
Voted
BMCBI
2005
97views more  BMCBI 2005»
15 years 14 days ago
Evolutionary distance estimation and fidelity of pair wise sequence alignment
Background: Evolutionary distances are a critical measure in comparative genomics and molecular evolutionary biology. A simulation study was used to examine the effect of alignmen...
Michael S. Rosenberg
SCFBM
2008
107views more  SCFBM 2008»
15 years 1 days ago
Microbial Diagnostic Array Workstation (MDAW): a web server for diagnostic array data storage, sharing and analysis
Background: Microarrays are becoming a very popular tool for microbial detection and diagnostics. Although these diagnostic arrays are much simpler when compared to the traditiona...
Joy Scaria, Aswathy Sreedharan, Yung-Fu Chang
107
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BMCBI
2010
121views more  BMCBI 2010»
14 years 10 months ago
Computing DNA duplex instability profiles efficiently with a two-state model: trends of promoters and binding sites
Background: DNA instability profiles have been used recently for predicting the transcriptional start site and the location of core promoters, and to gain insight into promoter ac...
Miriam R. Kantorovitz, Zoi Rapti, Vladimir Gelev, ...
137
Voted
ECIR
2011
Springer
14 years 4 months ago
Combining Global and Local Semantic Contexts for Improving Biomedical Information Retrieval
In the context of biomedical information retrieval (IR), this paper explores the relationship between the document’s global context and the query’s local context in an attempt ...
Duy Dinh, Lynda Tamine