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108
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BMCBI
2008
130views more  BMCBI 2008»
15 years 20 days ago
Gene Prospector: An evidence gateway for evaluating potential susceptibility genes and interacting risk factors for human diseas
Background: Millions of single nucleotide polymorphisms have been identified as a result of the human genome project and the rapid advance of high throughput genotyping technology...
Wei Yu, Anja Wulf, Tiebin Liu, Muin J. Khoury, Mar...
69
Voted
BMCBI
2008
98views more  BMCBI 2008»
15 years 20 days ago
Assessing probe-specific dye and slide biases in two-color microarray data
Background: A primary reason for using two-color microarrays is that the use of two samples labeled with different dyes on the same slide, that bind to probes on the same spot, is...
Ruixiao Lu, Geun-Cheol Lee, Michael Shultz, Chris ...
110
Voted
BMCBI
2006
107views more  BMCBI 2006»
15 years 18 days ago
Simplifying gene trees for easier comprehension
Background: In the genomic age, gene trees may contain large amounts of data making them hard to read and understand. Therefore, an automated simplification is important. Results:...
Paul-Ludwig Lott, Marvin Mundry, Christoph Sassenb...
BMCBI
2006
108views more  BMCBI 2006»
15 years 18 days ago
A new pooling strategy for high-throughput screening: the Shifted Transversal Design
Background: In binary high-throughput screening projects where the goal is the identification of low-frequency events, beyond the obvious issue of efficiency, false positives and ...
Nicolas Thierry-Mieg
97
Voted
BMCBI
2006
186views more  BMCBI 2006»
15 years 18 days ago
Systematic gene function prediction from gene expression data by using a fuzzy nearest-cluster method
Background: Quantitative simultaneous monitoring of the expression levels of thousands of genes under various experimental conditions is now possible using microarray experiments....
Xiaoli Li, Yin-Chet Tan, See-Kiong Ng