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» Comparative genome assembly
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103
Voted
CF
2006
ACM
15 years 4 months ago
The potential of the cell processor for scientific computing
The slowing pace of commodity microprocessor performance improvements combined with ever-increasing chip power demands has become of utmost concern to computational scientists. As...
Samuel Williams, John Shalf, Leonid Oliker, Shoaib...
94
Voted
BMCBI
2008
78views more  BMCBI 2008»
15 years 18 days ago
A new protein linear motif benchmark for multiple sequence alignment software
Background: Linear motifs (LMs) are abundant short regulatory sites used for modulating the functions of many eukaryotic proteins. They play important roles in post-translational ...
Emmanuel Perrodou, Claudia Chica, Olivier Poch, To...
132
Voted
BMCBI
2010
143views more  BMCBI 2010»
15 years 18 days ago
Shape based kinetic outlier detection in real-time PCR
Background: Real-time PCR has recently become the technique of choice for absolute and relative nucleic acid quantification. The gold standard quantification method in real-time P...
Davide Sisti, Michele Guescini, Marco B. L. Rocchi...
BMCBI
2010
152views more  BMCBI 2010»
15 years 18 days ago
Apples and oranges: avoiding different priors in Bayesian DNA sequence analysis
Background: One of the challenges of bioinformatics remains the recognition of short signal sequences in genomic DNA such as donor or acceptor splice sites, splicing enhancers or ...
Jens Keilwagen, Jan Grau, Stefan Posch, Ivo Grosse
94
Voted
BMCBI
2007
106views more  BMCBI 2007»
15 years 18 days ago
Constructing a meaningful evolutionary average at the phylogenetic center of mass
Background: As a consequence of the evolutionary process, data collected from related species tend to be similar. This similarity by descent can obscure subtler signals in the dat...
Eric A. Stone, Arend Sidow