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» Comparative genome assembly
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BMCBI
2008
101views more  BMCBI 2008»
15 years 18 days ago
Reranking candidate gene models with cross-species comparison for improved gene prediction
Background: Most gene finders score candidate gene models with state-based methods, typically HMMs, by combining local properties (coding potential, splice donor and acceptor patt...
Qian Liu, Koby Crammer, Fernando C. N. Pereira, Da...
BMCBI
2010
139views more  BMCBI 2010»
15 years 18 days ago
CMASA: an accurate algorithm for detecting local protein structural similarity and its application to enzyme catalytic site anno
Background: The rapid development of structural genomics has resulted in many "unknown function" proteins being deposited in Protein Data Bank (PDB), thus, the functiona...
Gong-Hua Li, Jing-Fei Huang
86
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BMCBI
2008
105views more  BMCBI 2008»
15 years 18 days ago
Improving the prediction of mRNA extremities in the parasitic protozoan Leishmania
Background: Leishmania and other members of the Trypanosomatidae family diverged early on in eukaryotic evolution and consequently display unique cellular properties. Their appare...
Martin Smith, Mathieu Blanchette, Barbara Papadopo...
BMCBI
2006
161views more  BMCBI 2006»
15 years 16 days ago
A method for rapid similarity analysis of RNA secondary structures
Background: Owing to the rapid expansion of RNA structure databases in recent years, efficient methods for structure comparison are in demand for function prediction and evolution...
Na Liu, Tianming Wang
121
Voted
BMCBI
2005
86views more  BMCBI 2005»
15 years 11 days ago
Confirmation of human protein interaction data by human expression data
Background: With microarray technology the expression of thousands of genes can be measured simultaneously. It is well known that the expression levels of genes of interacting pro...
Andreas Hahn, Jörg Rahnenführer, Priti T...