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ISCAPDCS
2007
15 years 1 months ago
Architectural requirements of parallel computational biology applications with explicit instruction level parallelism
—The tremendous growth in the information culture, efficient digital searches are needed to extract and identify information from huge data. The notion that evolution in silicon ...
Naeem Zafar Azeemi
BMCBI
2010
98views more  BMCBI 2010»
15 years 18 days ago
An optimized TOPS+ comparison method for enhanced TOPS models
nd: Although methods based on highly abstract descriptions of protein structures, such as VAST and TOPS, can perform very fast protein structure comparison, the results can lack a...
Mallika Veeramalai, David Gilbert, Gabriel Valient...
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BMCBI
2010
102views more  BMCBI 2010»
15 years 18 days ago
Identification of recurrent regions of copy-number variants across multiple individuals
Background: Algorithms and software for CNV detection have been developed, but they detect the CNV regions sample-by-sample with individual-specific breakpoints, while common CNV ...
Teo Shu Mei, Agus Salim, Stefano Calza, Ku Chee Se...
BMCBI
2010
121views more  BMCBI 2010»
15 years 18 days ago
A Markov blanket-based method for detecting causal SNPs in GWAS
Background: Detecting epistatic interactions associated with complex and common diseases can help to improve prevention, diagnosis and treatment of these diseases. With the develo...
Bing Han, Meeyoung Park, Xue-wen Chen
BMCBI
2008
200views more  BMCBI 2008»
15 years 17 days ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia