Abstract. One phylogeny-based approach to horizontal gene transfer (HGT) detection entails comparing the topology of a gene tree to that of the species tree, and using their differ...
Abstract. An important problem in biology is to understand correspondences between mRNA microarray levels and mass spectrometry peptide counts. Recently, a compendium of mRNA expre...
Protein sequence alignments are more reliable the shorter the evolutionary distance. Here, we align distantly related proteins using many closely spaced intermediate sequences as ...
The Smith-Waterman algorithm for local sequence alignment is one of the most important techniques in computational molecular biology. This ingenious dynamic programming approach w...
With the exponential growth of biological sequence databases, it has become critical to develop effective techniques for storing, querying, and analyzing these massive data. Suffi...