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BMCBI
2007
97views more  BMCBI 2007»
14 years 9 months ago
In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation
Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
Tineke Casneuf, Yves Van de Peer, Wolfgang Huber
BMCBI
2007
146views more  BMCBI 2007»
14 years 9 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
BMCBI
2007
129views more  BMCBI 2007»
14 years 9 months ago
HoughFeature, a novel method for assessing drug effects in three-color cDNA microarray experiments
Background: Three-color microarray experiments can be performed to assess drug effects on the genomic scale. The methodology may be useful in shortening the cycle, reducing the co...
Hongya Zhao, Hong Yan
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BMCBI
2010
155views more  BMCBI 2010»
14 years 9 months ago
A bi-ordering approach to linking gene expression with clinical annotations in gastric cancer
Background: In the study of cancer genomics, gene expression microarrays, which measure thousands of genes in a single assay, provide abundant information for the investigation of...
Fan Shi, Christopher Leckie, Geoff MacIntyre, Izha...
BMCBI
2007
128views more  BMCBI 2007»
14 years 9 months ago
Compression-based classification of biological sequences and structures via the Universal Similarity Metric: experimental assess
Background: Similarity of sequences is a key mathematical notion for Classification and Phylogenetic studies in Biology. It is currently primarily handled using alignments. Howeve...
Paolo Ferragina, Raffaele Giancarlo, Valentina Gre...