959 search results - page 179 / 192 » Comparative genome assembly |
BMCBI
2008
14 years 9 months ago
2008
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
BMCBI
2008
14 years 9 months ago
2008
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
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BMCBI
2008
14 years 9 months ago
2008
Background: Alternative splicing is a major contributor to the diversity of eukaryotic transcriptomes and proteomes. Currently, large scale detection of alternative splicing using...
BMCBI
2010
14 years 9 months ago
2010
Background: Genome sequencing projects have expanded the gap between the amount of known protein sequences and structures. The limitations of current high resolution structure det...
BMCBI
2007
14 years 9 months ago
2007
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...