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BMCBI
2002
188views more  BMCBI 2002»
14 years 9 months ago
The limit fold change model: A practical approach for selecting differentially expressed genes from microarray data
Background: The biomedical community is developing new methods of data analysis to more efficiently process the massive data sets produced by microarray experiments. Systematic an...
David M. Mutch, Alvin Berger, Robert Mansourian, A...
BIOINFORMATICS
2007
190views more  BIOINFORMATICS 2007»
14 years 9 months ago
Towards clustering of incomplete microarray data without the use of imputation
Motivation: Clustering technique is used to find groups of genes that show similar expression patterns under multiple experimental conditions. Nonetheless, the results obtained by...
Dae-Won Kim, Ki Young Lee, Kwang H. Lee, Doheon Le...
BMCBI
2008
181views more  BMCBI 2008»
14 years 8 months ago
Assessing batch effects of genotype calling algorithm BRLMM for the Affymetrix GeneChip Human Mapping 500 K array set using 270
Background: Genome-wide association studies (GWAS) aim to identify genetic variants (usually single nucleotide polymorphisms [SNPs]) across the entire human genome that are associ...
Huixiao Hong, Zhenqiang Su, Weigong Ge, Leming M. ...
WABI
2010
Springer
167views Bioinformatics» more  WABI 2010»
14 years 7 months ago
Quantifying the Strength of Natural Selection of a Motif Sequence
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
Chen-Hsiang Yeang
WABI
2010
Springer
170views Bioinformatics» more  WABI 2010»
14 years 7 months ago
Haplotypes versus Genotypes on Pedigrees
Abstract. Genome sequencing will soon produce haplotype data for individuals. For pedigrees of related individuals, sequencing appears to be an attractive alternative to genotyping...
Bonnie Kirkpatrick